Synthesis of chromones, annulated with oxygen-containing heterocycles with two hetero atoms at C(7)-C(8) bond

Tatyana Shokol; Natalia Gorbulenko; Volodymyr Khilya

doi:10.17721/fujcV7I1P121-139

Authors

Tatyana Shokol
Natalia Gorbulenko
Volodymyr Khilya

DOI:

https://doi.org/10.17721/fujcV7I1P121-139

Keywords:

annulation, chromones, 6H-[1, 3]dioxolo[4, 5-h]chromen-6-one, 2, 3-dihydro-7H-[1, 4]dioxino[2, 3-h]chromen-7-one, 3, 4-dihydro-2H, 8H-[1, 4]dioxepino[2, 3-h]chromen-8-one, 3-dihydro-1H, 7H-chromeno[7, 8-b][1, 4]oxazin-7-one, 4H, 12H-pyrano[2, 3-a]phenoxazine-4-one

Abstract

The present review represented the advanced synthetic strategies for chromones annulated at the C(7)-C(8) bond with five-membered, six-membered, and seven-membered oxygen-containing heterocycles with two heteroatoms, such as 6H-[1,3]dioxolo[4,5-h]chromen-6-one, 2,3-dihydro-7H-[1,4]dioxino[2,3-h]chromen-7-one, 3,4-dihydro-2H,8H-[1,4]dioxepino[2,3-h]chromen-8-one, 2,3-dihydro-1H,7H-chromeno[7,8-b][1,4]oxazin-7-one, 4H,12H-pyrano[2,3-a]phenoxazine-4-one and 9,10-dihydro-4H,8H-chromeno[8,7-e][1,3]oxazin-4-one. The biological activity of naturally occurring and modified synthetic fused hetarenochromones has been also highlighted.

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